Researcher • Transcriptomics • Bioinformatics

Dasari Abhilash

PhD Researcher at IIT Delhi

Specializing in Transcriptomics (Bulk, single cell and spatial)

Bulk RNA-seq Single-cell RNA-seq Spatial transcriptomics
Dasari Abhilash

Research focus

  • Bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics
  • Alternative splicing and transcript isoform analysis
  • Bioinformatics pipelines and data visualization
  • Teaching, mentoring, and scientific communication
View Publications Contact

Research journey

Research Experience

Student Exchange Program

IHU-ICAN, Sorbonne University, Paris, France

Feb 2025 - July 2025

Working with Dr. Maharaja Ponniah and Dr. Nadine Suffee on discovering novel biomarkers of atrial cardiomyopathy using imagery and tissue biology.

PhD Thesis Project (Bioinformatics)

Indian Institute of Technology Delhi

September 2020 - Present

Working with Dr. Ishaan Gupta on Dissecting the role of alternative splicing in respiratory and hepatobiliary pathology.

M.Sc Thesis Project (Genomics)

University of Hyderabad

May 2019 - May 2020

Working with Dr. Vivek T to discover the genes underlying tolerance against cry toxin in Achaea Janata.

Summer Research Intern (Computational Biology)

University of Hyderabad

May 2018 - June 2018

Worked with Dr. P Manimaran on Chaos Game Representation (CGR) and wrote a Python script for CGR applications.

Summer Research Intern

University of Hyderabad

May 2016 - June 2016

Worked with Prof. S. Rajagopal on metabolite interactions with Human Serum Albumin using fluorescence spectroscopy and SPR.

Selected work

Publications

First / Co-first Author

  • Tanwar, P., Bhattacharya, D., Dasari, A., Bijwe, M., Rana, R., Gupta, I. and Minocha, S., 2024. Dynamic gene expression pattern in zebrafish gallbladder: an experimental study. International Journal of Surgery, 110(12), pp.7585-7589. (DOI)
  • Srivastava, P.P., Dasari, A., Kumar, S., Gupta, I., Jain, D. and Minocha, S., 2025. Epigenetic co-regulator HCF-1 promotes lung cancer via O-GlcNAcylation-dependent pathways. Molecular Therapy Oncology, 33(4). (DOI)
  • Budhraja, A., Basu, A., Gheware, A., Abhilash, D., Rajagopala, S., Pakala, S., Sumit, M., Ray, A., Subramaniam, A., Mathur, P. and Nambirajan, A., 2022. Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality. Disease Models & Mechanisms, 15(5), p.dmm049572. (DOI)
  • Basu, A., Budhraja, A., Abhilash, D. and Gupta, I., 2021. Novel omics technology driving translational research in precision oncology. Advances in Genetics, 108, pp.81-145. (DOI)

Second Author

  • Saxena, V., Abhilash, D., Budhraja, A., Dey, S., Tiwari, P., Mohan, A., Gupta, I. and Kumar, S., 2026. RNA sequencing reveals differential expression of circular RNAs in human small cell lung cancer. Scientific Reports. (DOI)
  • Dhania, N.K., Chauhan, V.K., Abhilash, D., Thakur, V., Chaitanya, R.K., Dutta-Gupta, S. and Dutta-Gupta, A., 2021. Gut-specific arylphorin mediates midgut regenerative response against Cry-induced damage in Achaea janata. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 255, p.110600. (DOI)

For the complete list of publications, preprints and links to full-texts, download the CV below.

Download CV (PDF)

Background and milestones

Education

Education

  • PhD, Department of Biochemical Engineering and Biotechnology — Indian Institute of Technology Delhi (Sep 2020 - Present)
  • Integrated M.Sc. in Systems Biology — University of Hyderabad (Jul 2015 - May 2020). GPA: 7.73/10.0
  • Higher Secondary School Certificate — Sri Chaitanya junior kalasala (Jun 2013 - May 2015). Percentage: 93.60 (Biology, Physics, Chemistry)
  • Secondary School Certificate — Manair High School (Jun 2012 - Apr 2013). CGPA: 8.8

Academic Achievements

  • CSIR-UGC: Secured ranks 97 and 115 in Joint CSIR-UGC Junior Research Fellowship and Eligibility for Lectureship (NET) exams (Dec 2018, 2019)
  • IIT-JAM: Secured ranks 454 (Biological Sciences) and 687 (Biotechnology)
  • GATE-2020: Rank 292 (Life Sciences)

Service and engagements

Leadership & Activities

Leadership

  • CAIC-PG Convenor: Co-curricular and Academic Interaction Council (PhD Convenor) 2024-25, IIT Delhi
  • Research Scholar Forum (RSF) executive committee member 2023-24

Workshops & Symposium

  • Speaker at Spatial transcriptomics workshop conducted at ICGEB. Aug-2024
  • Poster presentation at Indian Cancer Genome Atlas (ICGA) - 2024
  • Human Cell Atlas Asia 2023 Meeting
  • DBEB BIOSPHERE symposium (2023, 2024) — Oral and Poster presentations
  • National Symposium on Frontiers in Biomedical Research (Nov 2022)
  • IUBMB Focused Meeting – Biochemistry and Molecular Biology of RNA Viruses (Nov 2022)
  • Won first prize in Hackbiome, a bioscience hackathon organised by the Bioscience Society, NIT Rourkela (Apr 2021)
  • 2nd Workshop of Advanced Bioinformatics: Network Medicine (Feb 2021) organised by LAVIS - Institute of Neurobiology-Juriquilla, RiaBio
  • GIAN workshop on "Applied photosynthesis: putting nature into work" (Sep 2019), University of Hyderabad
  • Workshop "New vistas in drug discovery" (Mar 2019), University of Hyderabad
  • Workshop "Data Science in Biomedical Research" (Dec 2018), University of Hyderabad
  • Rural immersion camp 2018 (NCRI with UoH and MHRD)
  • GIAN workshop "Systems Biology for Drug Discovery and Personalized Medicine" (Jul 2018)
  • Systems, Synthetic, Chemical symposium (2017), Bose Institute, Kolkata
  • Participated in MIMASA science quiz preliminaries (2016, 2017) conducted by IISER Pune

Beyond the lab

Hobbies

Running (10 km), Swimming, Cycling

Teaching and mentoring

Teaching & Mentor Experience

  • Teaching: Responsible for teaching laboratory sessions to undergraduate students for the BBL434 - Bioinformatics course in 2022 and 2023.
  • Mentor: Supervised 3 B.Tech and 2 M.S. (Research) students in their final-year projects and mentored several research interns from 2022 to 2026.

Tooling and methods

Skills & Expertise

Programming Languages

  • R (tidyverse, Bioconductor)
  • Python (pandas, NumPy, SciPy)
  • Bash (shell scripting)

Bioinformatics & Transcriptomics

  • Bulk RNA-seq (alignment, quantification, differential expression)
  • Single-cell RNA-seq (Seurat/Scanpy)
  • Spatial transcriptomics analysis; cell type deconvolution
  • Transcript isoform / alternative splicing analysis

NGS Tools & Pipelines

  • FASTQ processing (FastQC, Trimmomatic)
  • Alignment (STAR, HISAT2)
  • Quantification (featureCounts, Salmon)
  • Workflow automation (Snakemake/Nextflow)

Data Visualization & Statistics

  • ggplot2, ComplexHeatmap
  • Statistical modeling, exploratory data analysis

Computational Environment

  • Linux/UNIX systems
  • HPC/cluster computing
  • Version control (Git)

Experimental & Languages

  • Gel Electrophoresis, Western Blot, Bacterial culture handling, Microscopy, PCR
  • English, Hindi, Telugu (Reading, Writing and Speaking)

Get in touch

Contact

Lab 232A, Block-1, DBEB, IIT Delhi, Hauz Khas, New Delhi. PIN:110016

abhilashdasari.10@gmail.com

+91-8688964492

Download CV